Πηγαίνετε εκτός σύνδεσης με την εφαρμογή Player FM !
Episode 131 (Dr Alexandra Sullivan)
Manage episode 408522549 series 2876373
Parenting Practices May Buffer the Impact of Adversity on Epigenetic Age Acceleration Among Young Children With Developmental Delays
Alexandra D W Sullivan, Anne K Bozack, Andres Cardenas, Jonathan S Comer, Daniel M Bagner, Rex Forehand, Justin Parent
Affiliations expand
- PMID: 37733001
- PMCID: PMC10626625 (available on 2024-09-21)
- DOI: 10.1177/09567976231194221
Abstract
This study examined whether children exposed to adversity would exhibit lower epigenetic age acceleration in the context of improved parenting. Children with developmental delays and externalizing behavior problems (N = 62; Mage = 36.26 months; 70.97% boys, 29.03% girls; 71% Latinx, 22.6% Black) were drawn from a larger randomized controlled trial (RCT), which randomized them to receive Internet-delivered parent-child interaction therapy (iPCIT; n = 30) or community referrals as usual (RAU; n = 32).
Epigenetic age acceleration was estimated with the pediatric buccal epigenetic clock, using saliva.
Adversity was assessed using parent, family, and neighborhood-level cumulative-risk indicators.
Adversity interacted with Time 2 (T2) observations of positive and negative-parenting practices to predict epigenetic age acceleration 1.5 years later, regardless of treatment assignment. Children exposed to more adversity displayed lower epigenetic age acceleration when parents evidenced increased positive (b = -0.15, p = .001) and decreased negative (b = -0.12, p = .01) parenting practices.
163 επεισόδια
Manage episode 408522549 series 2876373
Parenting Practices May Buffer the Impact of Adversity on Epigenetic Age Acceleration Among Young Children With Developmental Delays
Alexandra D W Sullivan, Anne K Bozack, Andres Cardenas, Jonathan S Comer, Daniel M Bagner, Rex Forehand, Justin Parent
Affiliations expand
- PMID: 37733001
- PMCID: PMC10626625 (available on 2024-09-21)
- DOI: 10.1177/09567976231194221
Abstract
This study examined whether children exposed to adversity would exhibit lower epigenetic age acceleration in the context of improved parenting. Children with developmental delays and externalizing behavior problems (N = 62; Mage = 36.26 months; 70.97% boys, 29.03% girls; 71% Latinx, 22.6% Black) were drawn from a larger randomized controlled trial (RCT), which randomized them to receive Internet-delivered parent-child interaction therapy (iPCIT; n = 30) or community referrals as usual (RAU; n = 32).
Epigenetic age acceleration was estimated with the pediatric buccal epigenetic clock, using saliva.
Adversity was assessed using parent, family, and neighborhood-level cumulative-risk indicators.
Adversity interacted with Time 2 (T2) observations of positive and negative-parenting practices to predict epigenetic age acceleration 1.5 years later, regardless of treatment assignment. Children exposed to more adversity displayed lower epigenetic age acceleration when parents evidenced increased positive (b = -0.15, p = .001) and decreased negative (b = -0.12, p = .01) parenting practices.
163 επεισόδια
Tutti gli episodi
×Καλώς ήλθατε στο Player FM!
Το FM Player σαρώνει τον ιστό για podcasts υψηλής ποιότητας για να απολαύσετε αυτή τη στιγμή. Είναι η καλύτερη εφαρμογή podcast και λειτουργεί σε Android, iPhone και στον ιστό. Εγγραφή για συγχρονισμό συνδρομών σε όλες τις συσκευές.