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Modern Healthspan

Modern Healthspan

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Our channel provides longevity, anti-aging and health information. We interview experts in their field to get the latest information in the longevity space. You can also come to our YouTube channel for more information here https://www.youtube.com/channel/UCLFEKx_LchTLy_XwjPToJ3A
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Here Dr Trommelen talks about practical take aways from his study. How much protein should we eat, how often and what type is best. He also talks about his personal protocol. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Department of Human Biology at Maastricht University. He is involved in research and education …
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Here Dr Trommelen talks about how the MPS continues for more than 12 hours, because of the presence of amino acids in the blood, however, mTOR does not appear to be activated and autophagy is not suppressed and provides his explanation for these findings. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Department of …
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Here Dr Trommelen talks about the amount of protein required to initiate MPS, what muscle break down is and how MPS is measured. Key take away: It is muscle synthesis which determines muscle mass much more then breakdown as breakdown remains in a very tight range. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Depar…
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Here Dr Trommelen talks about exercise and protein and how they are related to muscle protein synthesis. The importance of having both, the time window for MPS and the training stimuli required. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Department of Human Biology at Maastricht University. He is involved in res…
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Here Dr Trommelen talks about the background to the study, the major results and the type of protein used. 🌐Links in this episode Dr Jorn Trommelen works as an Assistant Professor at the Department of Human Biology at Maastricht University. He is involved in research and education regarding the impact of exercise and nutrition on muscle mass and fu…
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Here Dr Joffrey discusses Medicine 3.0 - how you can take control of your own health and his top 10 supplements (and three drugs) for longevity. 🌐Links in this episode Dr Joffrey's podcast on aging - free copy of his book, Longevity for Busy People is available for download from there. https://sapiopodcast.com/ Consumer Labs https://www.consumerlab…
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Here Dr Joffrey discusses sleep, how important it is and some tips for getting the best sleep. 🌐Links in this episode Dr Joffrey's podcast on aging - free copy of his book, Longevity for Busy People is available for download from there. https://sapiopodcast.com/ Consumer Labs https://www.consumerlab.com/ Renue by Science all 10% discount with code …
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Here Dr Joffrey discusses exercise for longevity and how it is different from exercise for other purposes including what is the minimum effective dose. He also talks about cardiovascular disease and why we should not die from it. 🌐Links in this episode Dr Joffrey's podcast on aging - free copy of his book, Longevity for Busy People is available for…
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Here Dr Joffrey discusses the keys to a healthy diet. Time restricted feeding, controlling glucose in general and spikes in particular, and ensuring that you have sufficient protein. 🌐Links in this episode Dr Joffrey's podcast on aging - free copy of his book, Longevity for Busy People is available for download from there. https://sapiopodcast.com/…
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Here Dr Joffrey discusses his view on future of aging and the most promising technology that he sees which will make a difference. He also talks about Longevity Escape Velocity. 🌐Links in this episode Dr Joffrey's podcast on aging - free copy of his book, Longevity for Busy People is available for download from there. https://sapiopodcast.com/ Cons…
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Here Matt & Wade discuss lifestyle, nutrition and supplement strategies to support cognitive performance as we get older. The Ultimate Nutrition Bible can be found here https://ultimatenutritionsystem.com/modern Our code of Modern10 will already be applied. The code will also work for all BiOptimizer products. 🌐Links in this episode Renue by Scienc…
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Here Matt & Wade discuss saturated fats and proteins as part of the diet. The Ultimate Nutrition Bible can be found here https://ultimatenutritionsystem.com/modern Our code of Modern10 will already be applied. The code will also work for all BiOptimizer products. 🌐Links in this episode Renue by Science all 10% discount with code MHS https://renueby…
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The Ultimate Nutrition Bible can be found here https://ultimatenutritionsystem.com/modern Our code of Modern10 will already be applied. The code will also work for all BiOptimizer products. 🌐Links in this episode Renue by Science all 10% discount with code MHS https://renuebyscience.com/ Use SUBMHS for 15% on subscriptions 10% off DoNotAge all prod…
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Here Matt & Wade discuss how to structure a diet and some of the pitfalls that can happen in implementation. The Ultimate Nutrition Bible can be found here https://ultimatenutritionsystem.com/modern Our code of Modern10 will already be applied. The code will also work for all BiOptimizer products. 🌐Links in this episode Renue by Science all 10% dis…
  continue reading
 
Here Dr Sorrentino discusses his personal longevity protocol and also some of his current work and how this is targeted at moving discoveries into the clinic. Vincenzo Sorrentino is an Italian-born scientist in the fields of aging, mitochondrial biology and neuromuscular degeneration. He obtained his PhD Cum Laude at the University of Amsterdam on …
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Here Dr Sorrentino discusses mitochondria and muscle aging and results from trials of Urolithin A and NR in countering some of the ill effects. Vincenzo Sorrentino is an Italian-born scientist in the fields of aging, mitochondrial biology and neuromuscular degeneration. He obtained his PhD Cum Laude at the University of Amsterdam on LDL-cholesterol…
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Here Dr Sorrentino discusses proteostasis, how it goes wrong with age and how raising NAD levels can help. Vincenzo Sorrentino is an Italian-born scientist in the fields of aging, mitochondrial biology and neuromuscular degeneration. He obtained his PhD Cum Laude at the University of Amsterdam on LDL-cholesterol regulation by the ubiquitin-proteaso…
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Apologies for missing the last two release dates. Hopefully back on track now! Here Dr Sorrentino introduces trigonelline a methylated form of nicotinic acid which can boost NAD levels. He also talks about his work at Singapore and the translation of longevity science into the clinic. Vincenzo Sorrentino is an Italian-born scientist in the fields o…
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Here Dr Maroon, talks about some of the latest work that they are doing at Pittsburgh University on direct stimulation of the brain with magnetic pulses, light and ultra-sound. Dr Joseph Maroon is an American neurosurgeon, author, and triathlon athlete. He is the professor and vice chairman of the Department of Neurological Surgery at the Universit…
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Here Dr Maroon, talks about the supplements that he takes to help him with his exercise protocol. Dr Joseph Maroon is an American neurosurgeon, author, and triathlon athlete. He is the professor and vice chairman of the Department of Neurological Surgery at the University of Pittsburgh Medical Center and has been the team neuroscientist for the Pit…
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Here Dr Maroon, talks about stress, including eustress and distress and his way of handling stress (exercise!) Dr Joseph Maroon is an American neurosurgeon, author, and triathlon athlete. He is the professor and vice chairman of the Department of Neurological Surgery at the University of Pittsburgh Medical Center and has been the team neuroscientis…
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Here Dr Maroon, talks his personal diet and his thoughts on protein intake, sarcopenia, the ketogenic diet and omega-3 fatty acids. Dr Joseph Maroon is an American neurosurgeon, author, and triathlon athlete. He is the professor and vice chairman of the Department of Neurological Surgery at the University of Pittsburgh Medical Center and has been t…
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Here Dr Maroon, talks about research that he is working on with a colleague in India, Dr Pravat Mandal looking at ROS as a cause of Alzheimer's and glutathione as a possible preventative measure. Dr Joseph Maroon is an American neurosurgeon, author, and triathlon athlete. He is the professor and vice chairman of the Department of Neurological Surge…
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Here Dr Maroon, discusses his path to becoming a triathlete, his exercise protocol and his experience with hyperbaric oxygen therapy. Dr Joseph Maroon is an American neurosurgeon, author, and triathlon athlete. He is the professor and vice chairman of the Department of Neurological Surgery at the University of Pittsburgh Medical Center and has been…
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Here Dr Seranova talks about the supplements she takes, and a couple that she does not. Also sleeping and a hack for getting better deep sleep. The new brain supplement that Dr Seranova talks about is now available. Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD in Stem C…
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Here Dr Seranova talks about her diet and exercise and how she thinks about these. Some links are affiliate links so we will earn a commission when they are used to purchase products. Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD in Stem Cell Biology and Autophagy from t…
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Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD in Stem Cell Biology and Autophagy from the University of Birmingham, UK. 🌐Links in this episode NMN Bio website: https://nmnbio.co.uk/ NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency https://ww…
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Here Dr Seranova answers some questions on the paper from the first interview (https://youtu.be/fsuhtgKUZRg). Particular topics we discuss, mitochondria fragmentation, de novo pathway in neurons, difference between NR & NMN. Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD …
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Here Dr Seranova talks through her latest paper on the impact of NAD precursors (NR & NMN) on autophagy in human neuron Dr. Seranova is a serial entrepreneur, holds an MSc in Translational Neuroscience from the University of Sheffield and a PhD in Stem Cell Biology and Autophagy from the University of Birmingham, UK. 🌐Links in this episode NMN Bio …
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Here Dr Gibala talks how to think about exercise routines and nutrition as well as sharing his own protocol and the current work of his lab Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In a…
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Here Dr Gibala talks about what is VO2max, why it is important, how to measure and improve it. Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the …
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Here Dr Gibala introduces interval training and discusses the various styles, and the benefits. Dr Martin Gibala is a Professor at McMaster University where his research examines the effects of exercise at the molecular to whole body level in both healthy individuals and people with chronic diseases. In addition to basic, mechanistic studies on the…
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Here Dr Patel talks about his topical glutathione treatment Glutaryl and the recent trial that was conducted at McGill University. Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for over three decades, Patel is an internationally recognized expert, cons…
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Here Dr Patel talks about the changes that happen with glutathione as we age, why it is important and what we can do to restore the levels. Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for over three decades, Patel is an internationally recognized exp…
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Here Dr Patel talks about glutathione's major two functions in the body, as an antioxidant and a detoxifier. He also discusses measuring our glutathione levels and what would be a good value to aim for. Dr. Nayan Patel is an alumnus of the University Of Southern California School Of Pharmacy, where he now serves as adjunct faculty. A pharmacist for…
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Here Dr Conlon talks about her personal protocol, that she has decided on as a data driven scientist. We also discuss the next steps for Nuchido as a longevity company. Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive in…
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Here Dr Conlon talks about the human trial that she sponsored to evaluate the benefits of Time+ on humans. Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive innovation in the field of aging, rejuvenation and healthspan. D…
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Here Dr Conlon talks through all the components of Nuchido Time+ and how they fit into the strategy of restoring NAD by activating the cell's natural mechanisms. Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive innovatio…
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Here Dr Conlon explains the biochemistry behind Nuchido Time+ and how it activates the salvage pathway through NAMPT to replenish cellular NAD in sustainable way. Dr Nichola Conlon is a molecular biologist specialising in the study of cellular aging. After a career in drug development, she founded Nuchido Laboratories to deliver disruptive innovati…
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Here Professor Gorbunova about the naked mole rat and bowhead whale and what adaptions they have to enable them to live longer. From this she discusses how these adaptions might be translated into interventions for humans. Dr Vera Gorbunova is a biologist. As the Doris Johns Cherry Professor at the University of Rochester, she identified high molec…
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Here Professor Gorbunova talks about hyaluronic acid, what it is and why it is different in naked mole rats. She also talks about a trial that she performed where the gene for HA was placed in mice. Finally we talk about how this could be translated into clinical usage. Dr Vera Gorbunova is a biologist. As the Doris Johns Cherry Professor at the Un…
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Here Professor Gorbunova talks about the two functions of SIRT6, deacetylation and ribosylation, the importance of them and how they can be activated. She also touches on chromatin remodeling and Yamanaka factors. Dr Vera Gorbunova is a biologist. As the Doris Johns Cherry Professor at the University of Rochester, she identified high molecular weig…
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Here Professor Gorbunova talks about the key activities of SIRT6 that are involved with longevity, particularly DNA repair and the suppression of transposons. Dr Vera Gorbunova is a biologist. As the Doris Johns Cherry Professor at the University of Rochester, she identified high molecular weight hyaluronan as the key mediator of cancer resistance …
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In this video Dr Wang talks about the current state of trials and how the therapy might eventually look. Stan Wang is Founder and CEO of Thymmune Therapeutics, a cell therapy company working to address high unmet needs across immunology. Previously, Stan was Founding Chief Scientific Officer at Cellino Biotech, where he led R&D and application of i…
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In this episode Dr Wang explains about the thymus gland and his technology for not only restoring the thymus but building new thymuses from iPCSs at scale. Stan Wang is Founder and CEO of Thymmune Therapeutics, a cell therapy company working to address high unmet needs across immunology. Previously, Stan was Founding Chief Scientific Officer at Cel…
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Here Dr Tan talks about tocotrienols in bone health, what an appropriate dosage is and it is better not to take alpha tocopherol with the tocotrienols. Dr. Barrie Tan was formerly an assistant professor at the University of Massachusetts in Amherst (Chemistry, Food Science & Nutrition). His mission at American River Nutrition is to deliver the high…
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Here Dr Tan talks about the trails that have been run on tocotrienols and the results that have been seen. They have beneficial effects on a number of the markers of metabolic syndrome, such as the lipid panel and liver fat. Dr. Barrie Tan was formerly an assistant professor at the University of Massachusetts in Amherst (Chemistry, Food Science & N…
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Here Dr Tan introduces the forms of vitamin E, how they are different and why this matters. He also discusses why a fat based anti-oxidant is required and where alpha tocotrienol is found in nature. Dr. Barrie Tan was formerly an assistant professor at the University of Massachusetts in Amherst (Chemistry, Food Science & Nutrition). His mission at …
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Dr. Nathan Price is the Chief Scientific Officer of Thorne HealthTech. He is co-author with Lee Hood of The Age of Scientific Wellness, and has written articles for The Wall Street Journal, LA Times, and Scientific American. In 2019, he was named one of 10 Emerging Leaders in Health and Medicine by the National Academy of Medicine, and in 2021 he w…
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Here Dr Price talks about some of the things that they learned during the pilot exercises, about biomarkers and the gut microbiome. Dr. Nathan Price is the Chief Scientific Officer of Thorne HealthTech. He is co-author with Lee Hood of The Age of Scientific Wellness, and has written articles for The Wall Street Journal, LA Times, and Scientific Ame…
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