Adventures in sewing and life. We (Erin and Caroline from Spool & Spindle - an online fabric store located in Waterloo, Ontario) answer questions about sewing and other things that you want to know about.
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A podcast about dogs, dog training, dog health, knitting, spinning, fiber, yarn, stitch friends, and other adventures Gnat might enjoy. Gnat will share techniques and stories.
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The WonkyCast is an interview podcast hosted by Spindles and featuring appearances from actors, musicians, writers and more. You can find the latest episodes of The WonkyCast below, but you can also subscribe using the links below. And you can keep up to date with us on our facebook page too: http://www.facebook.com/TheWonkySpanner
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Authors J.A. Ironside and M.E. Vaughan talk about books, films and all aspects of speculative fiction, from the nuts and bolts of writing it, to its (occasionally) obscure origins.
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Of Slippers and Spindles - Fairy Tale Retellings and Adaptations in Books, Film, and Theatre
Drew Rothhaar, Cassie Greenlee
Join fairy tale enthusiasts Drew and Cassie as they discuss the world of film and literary adaptations! Each month they will choose a specific fairy tale, and each week they will discuss a different book, movie, or musical adaptation of that fairy tale, exploring the way authors and artists retell, change, twist, conserve, and diversify the same stories over and over.
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The Wonky Gamer podcast is a show hosted by Stef and features discussion with guest hosts on the latest happenings in the gaming world. You can find the latest episodes of The Wonky Gamer below, but you can also subscribe using the links below. And you can keep up to date with us on our facebook page too: http://www.facebook.com/TheWonkySpanner
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WASTOIDS is a pop cult dedicated to the thrill of the weird. Microdose podcast episodes and videos at WASTOIDS.com. Call us with your strangest story any time at 1-877-WASTOIDS.
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A podcast with a focus on current and popular knitting patterns, yarns and online activities. Handspinning on a wheel and spindle are also active topics. Pixie Purls chats about pop-knitting-culture and the online knitting community.
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Oncotarget is a primarily oncology-focused, peer-reviewed, open access journal. Papers are published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed. Oncotarget is now indexed by MEDLINE, PubMed and PMC/PubMed. Read about the Oncotarget Scientific Integrity Process: https://www.oncotarget.com/scientific_integrity/
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John Grimsmo of Grimsmo Knives and John Saunders of NYC CNC discuss their success, struggles, goals and more as machinists, business owners and entrepreneurs.
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Welcome to The Clip Out, the must-listen podcast for Peloton and fitness enthusiasts! Each week, we dive deep into the world of Peloton, exploring the latest news, trends, and community stories that make Peloton a fitness phenomenon. From inspiring member experiences to updates on the newest features, our show keeps you connected with everything you need to know about Peloton. Join us as we celebrate the growing Peloton community and stay at the forefront of the fitness revolution. Tune in t ...
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Saint Craft Radio | Saints | Football | Craft Beer
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A UK based Fantasy AGE podcast, played by a group of writers and theatrical creators. New episodes coming soon!
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The official podcast of the Sleep Research Society (SRS). Purposed to disseminate and discuss the latest findings in Sleep and Circadian research.
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The latest album and E.P. reviews by New Zealand's Top Music Journalists. Each week we review four new releases that will keep you up to date on the best rock, indie, Americana, blues, Hip-Hop and Jazz albums.
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After a long break Cameron is back with his new version of the podcast. He is still reviewing mostly indie fantasy novels but he’s now doing it in his tractor. Cameron spends way too much time in said tractor and figured that since he was listening to a lot of audiobooks but had almost zero time to record episodes with his wife and friends like he used to he would put some of that tractor time to use and record podcast episodes again.
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The goal of this podcast is to talk with people within the U.S. Manufacturing space who are helping to grow and change the way that we do business. It is also to bring a new perspective on industrial technology, manufacturing strategy, and inspiration to an expanding market letting the world know we are here to stay. Be part of the Manufacturing Alliance and together we can MAKE AMERICAN MANUFACTURING GREAT AGAIN!
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An incredible journey of heartache and triumph. Follow us as a young lion loses his father at the paws of his uncle and a large stampede of wildebeests. Young lion leaves the crib because, fuck that. He befriends a meerkat and a warthog who convince him bugs are a delicacy and also he should go home to stop his uncle from making advances on his mom because that's super weird. Young lion is bugged out about the incest so he smokes a bit of sheesha with a mandrill and talks to his dead dad. Be ...
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Peloton Announces All-For-One Dates Plus Our Interview With Lindsey Spindle
1:25:56
1:25:56
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Peloton announces All-For-One dates. John Foley’s post-Peloton sell-off. LifeHacker writes about Peloton’s new $95 activation fee. Tips for accessing Peloton’s website when it doesn’t work. Peloton Quick Hits. Angelo/MetPro - When does cardio become TOO much cardio for perimenopausal women? Becs Gentry was ABC News. Selena Samuela discusses her mis…
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In 1967, Columbia decided to debut a new band called Moby Grape not just with an album—but also five simultaneously released 7-inch singles! Fall On You w/Changes Sitting By the Window w/Indifference 805 w/Mr. BluesOmaha/w Hey Sunday Hey Grandma w/Come in the Morning It might've been a dubious marketing plan, but it produced a ton of great music, a…
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BUFFALO, NY- August 14, 2024 – A new #casereport was #published in Oncotarget's Volume 15 on July 17, 2024, entitled, “Rapid but nondurable response of a BRAF exon 15 double-mutated spindle cell sarcoma to a combination of BRAF and MEK inhibitors.”As noted in the introduction of the Abstract, the BRAF V600E substitution predicts a cancer's sensitiv…
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Band Shirt Stories from Vicky Farewell and Weezer Historian Karl Koch | Band Shirt Day Podcast
34:18
On one hand, a band shirt is a simple everyday item, the kind of thing you might take for granted. But when you start thinking about it, the topic encompasses so much more: band shirts help us tell stories about ourselves and what music means to us. And that’s why we’re here: to think a little more about band shirts and the holiday invented to cele…
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Nada Surf may have broken in the '90s with the sardonic mega-hit "Popular," but songwriter Matthew Caws isn't big on living in the past. On the band's new album, Moon Mirror, out September 13th from New West Records, he sets his sights on the present moment, focusing on the anxieties, hopes, and fears of our age while never losing sight of the hope…
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Decoy Deloy is back with a news bulletin from the Hello Lincoln loft studio. In this episode, he shares some history and a new merch drop from People Under the Stairs, a legendary underground rap duo who have recently resurfaced at Hello Merch. Then, an interview with two more legends: Steve and Jeff McDonald of the mighty Redd Kross. Fresh off rel…
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Episode 428: All in the Details - How to Use Description in Speculative Fiction part 1
1:04:37
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Part 1 of a 2 part episode The dragons are back and gearing up for spooky season. This week, Jules and Madeleine take a look at the thorny issue of 'details'. Speculative fiction can, by it's very nature, require extensive world building which in turn requires plenty of detail. But how do you know what to include or exclude? How much detail should …
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Peloton's New Strength+ App is in Beta plus our interview with Gillian Robertson
1:09:59
1:09:59
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1:09:59
Peloton’s new Fall Schedule. Peloton’s Strength+ app is in beta. Blue Dots are now purple. Peloton debuts new Teams feature. Peloton CFO participating in tech conferences. Peloton Quick Hiits. Dr. Jenn - How to bounce back when your favorite fitness instructor leaves. Peloton cycling instructor Emma Lovewell has her baby! Peloton cycling instructor…
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TOPICS: Family vs business Aluminum fixtures Autodesk CAM Challenge IMTS 2024 planning Rego-Fix PG hydraulic pressing unit Wire EDM MachinesΑπό τον johngrimsmo
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TOPICS: Grimsmo's family vacation Alarms on Machines American Precision Museum in Vermont Kern toolsetter issues Okuma break detect issues Electropolishing metalsΑπό τον johngrimsmo
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Macrophage Migration Inhibitory Factor (MIF) and its homolog D-dopachrome Tautomerase (DDT) have been implicated as drivers of tumor progression in various cancers. Recent evidence suggests that MIF could be a therapeutic target in immune checkpoint inhibition (ICI) resistant melanomas; however, clinical evidence for MIF, and particularly for DDT, …
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BUFFALO, NY- August 28, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on August 26, 2024, entitled, “Inhibition of miR-10b treats metastatic breast cancer by targeting stem cell-like properties.”As stated within the Abstract of the paper, despite advances in breast cancer screening and treatment, the prognosis for metastatic…
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BUFFALO, NY- August 27, 2024 – A new #editorial was #published in Oncotarget's Volume 15 on August 26, 2024, entitled, “Artificial intelligence: A transformative tool in precision oncology.”Artificial intelligence (AI) is revolutionizing society and healthcare, opening new possibilities for precision medicine. In oncology, immunotherapy (IO) has si…
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BUFFALO, NY- August 26, 2024 – A new #editorial was #published in Oncotarget's Volume 15 on July 10, 2024, entitled, “Genotype matters: Personalized screening recommendations for germline CHEK2 variants.”Recognized as a moderate-risk gene, CHEK2—responsible for encoding the CHK2 protein, which plays a crucial role in the repair of DNA double-strand…
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Say Hello to Devo, Arms & Sleepers on Tour, Meet Tony Hawk's Creative Director Jaimie Muehlhausen
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Decoy Deloy is back with more Music News brought to you by Hello Merch. Here at Hello, we don’t mess around: we do merch, we do it right, and we put artists first. And this week, we’re pleased to announce a fresh new addition to the Hello fam: that’s right, the legendary DEVO is in the house. Formed in Akron, Ohio in 1973, DEVO has gone on to inspi…
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Is Peloton Phasing Out The Bike? Plus Our Interview With Catie Powell
1:17:32
1:17:32
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1:17:32
Peloton offers equipment removal…for some. Peloton launches Just Guidance. Kindle available on Peloton equipment. Peloton launches Wellness Marketplace. Peloton needs your help for beta testing. An overview of the PSL Pace Targets event. Peloton suffered partial outage. Details on the next Lululemon Members Weekend. Mariana Fernandez now a Tread re…
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BUFFALO, NY- August 21, 2024 – A new #editorial was #published in Oncotarget's Volume 15 on July 17, 2024, entitled, “Strategies to disrupt NKG2A:HLA-E interactions for improved anti-cancer immunity.”Two studies using CRISPR screens in cancer cells identified HLA-E as a critical negative regulator of NK cell interactions with cancer cells. Consiste…
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On their new album Oyster Cuts, Australian indie rockers Quivers blend jangle rock, synth-dappled new wave, and catchy indie-pop. Echoing the strum and chime of classic alt-acts like The Go-Betweens and R.E.M (they devoted their entire 2020 album to cover songs from the latter), Sam Nicholson (guitars), Bella Quinlan (bass), Michael Panton (guitars…
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BUFFALO, NY- August 19, 2024 – A new #review was #published in Oncotarget's Volume 15 on August 14, 2024, entitled, “The gut barrier as a gatekeeper in colorectal cancer treatment.”Colorectal cancer (CRC) is highly prevalent and a major cause of cancer-related deaths worldwide. The primary curative treatment for CRC is surgical resection of the aff…
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Peloton Inks Partnership with Google Fitbit Plus Our Interview with author Amanda McKinney
1:12:36
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1:12:36
Peloton inks partnership with Google Fitbit. Peloton sets their next earnings call. Peloton employee Nick Mead was Olympic closing ceremony flag bearer. How to make challenges work for you. Peloton has a special offer for NYC Marathon runners. Next Lulu Members weekend at PSNY is in September. Dr. Jenn - Coping with schedule changes. Jermain Johnso…
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TOPICS: Accounts receivable issues Okamoto surface grinder Rask blade issues New Willemin at SMWΑπό τον johngrimsmo
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Jazz legend Herbie Hancock's venture into the land of hip-hop beats and turntable scratches, "Rockit", was ubiquitous on the dance floor and MTV's rotation, but its origin story is more interesting than you might think. John and Marc dig into the grooves of this groundbreaking '80s staple on the latest episode of the Spindle. Call us anytime at 1-8…
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BUFFALO, NY- August 15, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on August 14, 2024, entitled, “A nanobody against the V-ATPase c subunit inhibits metastasis of 4T1-12B breast tumor cells to lung in mice.”The vacuolar H+-ATPase (V-ATPase) is an ATP-dependent proton pump that functions to control the pH of intracellular …
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BUFFALO, NY- August 12, 2024 – A new research perspective was published in Oncotarget's Volume 15 on July 16, 2024, entitled, “Targeting the multifaceted BRAF in cancer: New directions.”In cancer patients, BRAF-targeting precision therapeutics are effective against Class I BRAF alterations (p.V600 hotspot mutations) in tumors such as melanoma, thyr…
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Combining Regorafenib and TAS102 to Target Gastrointestinal Cancers and Overcome Cancer Stemness
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In this research paper, researchers demonstrate a promising new treatment option for refractory metastatic gastrointestinal cancers using a combination of two FDA-approved drugs.Researchers Jun Zhang, Lanlan Zhou, Shuai Zhao, and Wafik S. El-Deiry from Fox Chase Cancer Center and Brown University explore the potential of combining TAS102 (triflurid…
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This is Music News, brought to you by Hello Merch! This week, we're psyched to share new tie-dyes from ROAR, check out the news from visionary filmmaker David Lynch & mysterious vocalist Chrystabell, scope a new (archival) video from Get Up Kids, listen to new tunes from Torres & Fruit Bats, and reflect on recent bummer news from Ween. Call us anyt…
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Peloton Bike Removed From Rental Program Plus Pt. 2 Of Ross Rayburn
1:16:51
1:16:51
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Peloton Bike removed from rental Program. Peloton employee wins Gold at Olympics. An On-Demand outage. PSL and PSNY are hosting Pace Targets events. Hyatt adds Peloton to 800 locations. Lululemon adds new Peloton perks for members. Quick Hits. Angel/MetPro - How to tell if a strength class focuses on endurance or hypertrophy. Christine D’Ercole win…
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TOPICS: Time off with family Inbox zero Getting everything DONE What systems do you use? Smart AI stuff? Machines and processesΑπό τον johngrimsmo
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BUFFALO, NY- August 8, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on August 5, 2024, entitled, “Chemical complementarity of tumor resident, T-cell receptor CDR3s and renalase-1 correlates with increased melanoma survival.”As mentioned in the Abstract of this study, overexpression of the secretory protein renalase-1 negati…
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BUFFALO, NY - August 7, 2024 – A new #editorial paper was #published in Oncotarget's Volume 15 on July 12, 2024, entitled, “How to deal with runaway metastatic disease?”In this new editorial, Justine Paris and Guilhem Bousquet from Université Paris Cité, Université Sorbonne Paris Nord, and APHP, Hôpital Avicenne, Oncologie médical, discussed how th…
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BUFFALO, NY- August 5, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on July 12, 2024, entitled, “INT-1B3, an LNP formulated miR-193a-3p mimic, promotes anti-tumor immunity by enhancing T cell mediated immune responses via modulation of the tumor microenvironment and induction of immunogenic cell death.”In this study, resear…
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Decoy Deloy is back with music news you need to know. Up first, dive into classic progressive pop band 10cc's new merch collection at Hello Merch; then, dig into the Desert Daze 2024 lineup, featuring Jack White, Cigarettes After Sex, Say She She, Molchat Doma, and so many more. Then, give the claymation video for Stephen Malkmus (Pavement, The Jic…
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Kendall Toole Reveals Why She Left Peloton Plus Book Club With Ross Rayburn
1:24:49
1:24:49
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Kendall Toole’s classes not being purged…for now. Kendall offered more insight into her exit. Form Feedback comes to the Guide. Law firm perks include Pelotons at work. Introducing instructor high fives. Another store closing. Peloton Quick Hits. Dr. Jenn - Overcome your disinterest in Peloton. Becs Gentry gets honest. Emma Lovewell on maternity le…
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Episode 427: The Boys are Back in Town - the Dark Heart of the Superhero Genre
1:27:33
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Please note this episode contains spoilers for all the shows and books mentioned! It's the human in superhuman which is the interesting aspect of the superhero genre, which is why the genre is so good at holding up a dark mirror to the worst aspects of humanity as well as being aspiration. This week Jules and Madeleine delve into the murky waters o…
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My Bloody Valentine were a great band from the start, but the 1990 Glider EP broke their floodgates open, as Kevin Shields turned the band's mix of thick guitars, heavy bass, pounding drums, and heavenly vocals into a soundworld of its own. After a little bit of a summer hiatus, Marc Masters (author of High Bias: The Distorted History of the Casset…
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Decoy Deloy shines a light on Synthesizer, the brand new album from one of the wildest bands we've ever seen: A Place to Bury Strangers. For their 7th album, A Place to Bury Strangers decided to pull out all the stops: the 12” vinyl LP is packaged in a cover that can be assembled into a noise synthesizer. That’s right, the vinyl is packaged in a ci…
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BUFFALO, NY- July 26, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on July 19, 2024, entitled, “Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma.”Macrophage Migration Inhibitory Factor (MIF) and its homolog D-dopachrome Tautomerase (DDT) have been implicated as drivers of tumor progression across a va…
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Peloton Closes PSNY For 3 Weeks Plus Our Interview With Kayla Lippens!
1:19:57
1:19:57
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1:19:57
Peloton drops Guide price. Bryan Park Yoga Series. Peloton Studios 2024 closure dates. Peloton Quick Hits. Fueling for a marathon when you’re counting macros. What is Adrian Williams teasing? Jermaine Johnson taught his last live class before paternity leave. Logan Aldridge participated in Soldier Ride NYC. Alex Toussaint is hosting a shakeout run …
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TOPICS: Book recommendation: 6 Types Of Working Genius Venturi coolant sucker upper Normalizing steel for flatness Solar power for a shop? E-paper display: "#17 Using e-ink (epaper) Price Tags (Shelf Labels) for everyday needs" https://www.youtube.com/watch?v=BCkMu57S_YAΑπό τον johngrimsmo
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Episode 426: Change, Uncertainty and Unhappiness - making low stakes compelling
1:07:26
1:07:26
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Not every story can be or needs to be high octane intensity. In fact some of the best books are objectively quiet affairs. Low stakes does not mean low story or lack of compelling reading or viewing experience however. This week, Jules and Madeleine take a look at why low stakes can be just as enthralling as high stakes, and in many ways can provid…
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In the ever-evolving quest for effective cancer treatments, researchers are continuously exploring innovative combinatorial approaches that exploit the vulnerabilities of malignant cells. In a new study, researchers Benigno C. Valdez, Apostolia M. Tsimberidou, Bin Yuan, Yago Nieto, Mehmet A. Baysal, Abhijit Chakraborty, Clark R. Andersen, and Borje…
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BUFFALO, NY- July 24, 2024 – A new #research paper was #published in Oncotarget's Volume 15 on July 22, 2024, entitled, “Prevalence and impact of the KIT M541L variant in patients with mastocytosis.”Activating mutations in KIT, particularly D816V, have been associated with mastocytosis. Additionally, expression of heterozygous KIT M541L has been pr…
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