Τα καλύτερα Stemcell podcast (2024)

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Episode 153: Dr Ina Sonnen "It is possible to have a career and a family in science" 24:43

2y ago24:43

24:43

In this episode, Ina Sonnen, a researcher at the Hubrecht Institute in the Netherlands, is interviewed by Postdocoral researcher JF Darrigrand. Ina explains which are the big questions studied in her lab, notably how cells can communicate not only via the nature of signals they exchange but also through the dynamics of these signlas. She shares how…

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Episode 152: Prof Andrew Ewald "Understand the simple rules generating apparent complexity" 23:34

2+ y ago23:34

23:34

In today’s episode, Prof. Andrew Ewald, Director of the Cell Biology Department at the Johns Hopkins School of Medicine is interviewed by Inês Tomás. Prof Ewald explains how he transitionned from a background in physics to the field of cancer biology. He touches upon why cancer is such a specific type of disease, how cancer cells talk to each other…

1
Episode 151: Dr William Roman "Use your PhD as a platform" 16:38

3y ago16:38

16:38

In today’s episode, Dr. William Roman, a research associate at Stanford University, is interviewed by Dr. Davide Danovi. William explains how he is combining live cell imaging and quantitative approaches to answer fundamental questions in muscle biology. He shares some inspiring mentoring advice on how to let students use their PhDs as platforms to…

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Episode 150: Prof Shalev Itzkovitz "We can infer the design principles of organs" 29:23

3y ago29:23

29:23

In today’s episode, Shalev Itzkovitz, a professor at the Weizman Institute, Israel, is interviewed by Postdocoral researcher Georgina Goss. Shalev shares the discoveries of his lab on the design principles that shape and maintain metabolic organs such as the intestine and the liver. He explains the very advanced techniques used in modern biology, a…

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Episode 149: Professor Xin Chen-“We are very fascinated by this kind of ‘immortality’ of germ cells” 15:53

3y ago15:53

15:53

In today’s episode, Prof Xin Chen, a group leader at Johns Hopkins University in Baltimore, is interviewed by PhD student Daria Belokhvostova. Xin takes us into the world of germline stem cell epigenetics and how its regulation can influence the ability of these cells to divide asymmetrically. She shares her passion for the biology of germ cells an…

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Episode 148: Dr Allison Bardin- “Unexpected results lead to novel discoveries” 15:57

3y ago15:57

15:57

In today’s episode, Dr Allison Bardin, a group leader at Institut Curie, is interviewed by PhD student Vassia Salameti. Allison talks about how she got interested in asymmetric cell division while working on budding yeast, followed by her work on fly as a postdoc that derived her into the field to study cell fate acquisitions and stem cell biology.…

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Episode 147: Professor Yukiko Yamashita- “Junk DNA may not be all Junk” 16:27

3y ago16:27

16:27

In today’s episode, Prof Yukiko Yamashita, a group leader at Whitehead Institute for Biomedical Research, MIT, is interviewed by PhD student Joshua Reeves. Yukiko talks about how her lab got interested in understanding the possible mechanism of non siter chromatid segregation in germline cells. She talks about how they started looking at the intere…

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Episode 146: Prof Ludo Van Den Bosch– “Exciting time for researchers” 14:32

3y ago14:32

14:32

In today’s episode, Prof Ludo Van Den Bosch a group leader at VIB-KU Leuven Center for Brain & Disease Research, is interviewed by PhD student Abigail Isaacson. Ludo talks about his labs goal and how they use different model systems to understand disease as good as possible with goal to develop therapies. He also highlighted the importance of using…

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Episode 145: Prof Elena Ezhkova- “The more you try understand science the more interesting it gets” 15:39

3y ago15:39

15:39

In today’s episode, Prof Elena Ezhkova, a group leader at Icahn School of Medicine, is interviewed by PhD student Vassia Salameti. Elena talks about the potential of stem cells in therapy and how her interest developed towards understanding the role of epigenetic regulators in stem cell reprogramming. She shares about how companies are getting inte…

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Episode 144- Prof Filipe Pereira- "It's about defining what will keep you fueled for years" 19:07

3y ago19:07

19:07

In today’s episode, Prof Filipe Pereira, a professor at Lund University, Sweden, is interviewed by postdocoral researcher Jean-Francois Darrigrand. Filipe shares how he started his career in the fields of stem cells reprogramming and immunotherapy, as well as his experience working in the US and different european countries. Filipe also discusses a…

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Episode 143 -Prof Denis Duboule - "As long as people are happy in your lab, it's fine" 14:38

3y ago14:38

14:38

In today’s episode, Prof Denis Duboule, a professor of developmental biology at EPFL and Univeristy of Geneva is interviewed by PhD student Abigail Isaacson. Denis talks about how his first interest for mushrooms initiated his whole career in biology. He shares with us his fascination for the encoding of time in the genome, which ensures the proper…

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Episode 142 -Prof Dagmar Iber- "Don't play too safe and be lucky." 11:05

3+ y ago11:05

11:05

In today’s episode, Prof Dagmar Iber, a professor at ETH, Zurich, is interviewed by PhD student Vasiliki Salameti. Dagmar talks about the similarity between investment banking and academia . She describes her interest in modelling organogenesis and patterning systems. She discusses the importance of collaboration. She also advised students to take …

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Episode 141 - Dr Vikas Trivedi - “You get to learn things from people that you would not know” 18:47

3+ y ago18:47

18:47

In today’s episode, Dr Vikas Trivedi, a group leader at EMBL Barcelona, is interviewed by PhD student Prudence Lui. Vikas talks about his scientific journey and his research on using embryonic organoids to study self-organisation of cells. He describes the challenge in this field to use interdisciplinary approaches to study complex biological pheno…

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Episode 140- Dr Emma Rawlins "I'll look at stem cell in any systems" 21:49

3+ y ago21:49

21:49

In today’s episode, Dr Emma Rawlins, a senior group leader at the Gurdon Institute in University of Cambridge. She is interviewed by PhD student Elena Drudi. Emma talks about her research on stem cells in mammalian lungs using both mouse and human organoid models. She discusses the pros and cons of the two models. She describes her research interes…

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Episode 139 - Dr Vanessa Ribes - “We make bonds in thinking and developing ideas” 18:49

3+ y ago18:49

18:49

In today’s episode, Dr Vanessa Ribes, a group leader at Jacques Monod Institute, Paris, is interviewed by PhD student Victoria Tsang. Vanessa talks about her research on embryonic development of the spinal cord, its transcriptional regulation, the pathology of related congenital diseases, as well as cancers. She describes her long-time passion for …

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Episode 138 - Dr Carla Mulas - "Beyond mapping cell states and identities" 11:28

3+ y ago11:28

11:28

In today’s episode, Dr Carla Mulas, a postdoc in Stem Cell Institue at Cambridge University, is interviewed by PhD student Haneen Alsehi. Carla talks about her amazing research using biophysics to understand cell state transition. She discusses her journey in transiting from a biochemistry background to studying stem cells and their fate commitment…

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Episode 137 - Dr Kristina Haase - "These vessel systems are so beautiful!" 14:20

3+ y ago14:20

14:20

In today’s episode, Dr Kristina Haase, a group leader at EMBL Barcelona, is interviewed by PhD student Prudence Lui. Kristina talks about her amazing research on bioengineered vascular networks and what kept her motivated to work on this for years. She discusses some challenges to be considered when generating advanced vascularised experiment model…

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Episode 136 - Dr. Dominika Dziedzicka- "Differentiation propensity" 17:28

3+ y ago17:28

17:28

On today’s episode, Dr Dominika Dziedzicka, a postdoc working with Prof Ludovic Vallier from MRC Cambridge Stem Cell Institute. She is interviewed by Daria Belokhvostova, a PhD student in Centre of Stem Cells & Regenerative Medicine in King’s College London. Dominika talks about her PhD and recent postdoc work on human embryonic and induced pluripo…

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Episode 135 - Ieva Berzanskyte - "When I started understanding it more I grew fond of it." 17:41

3+ y ago17:41

17:41

In today’s episode, Ieva Berzanskyte, our own graduating PhD student at the Centre for Stem Cells and Regenerative Medicine at King’s College London, is interviewed by PhD student Inês Tomás. Ieva talks about her exciting work on growing stem cells from patient tissues, then turning them into neurons to find a cure for spinal cord injury. She share…

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Episode 134-Prof Michael Levin-"Learn the best and put them together in your own way" 14:44

3+ y ago14:44

14:44

On today’s episode, Prof Michael Levin, a renowned regenerative and developmental biologist of Tufts University and Wyss Institute at Harvard University, is interviewed by Dr Davide Danovi, a group leader in Centre of Stem Cells & Regenerative Medicine in King’s College London. Mike talks about his multi-disciplinary work in decoding bioelectrical …

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Episode 133 – Ana Pombo – “Every day I learn something.” 18:01

3+ y ago18:01

18:01

In today’s episode, Prof Ana Pombo, group leader at the Max Delbrück Center for Molecular Medicine in Berlin, is interviewed by PhD student Vasiliki Salameti. Ana talks about her pioneering work that enabled scientists to dissect how the genome is packaged inside cells and how this method is evolving with new single-cell technologies. She shares he…

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Episode 132 – Nicolas Rivron – “By understanding the embyro, you understand regeneration.” 20:16

3+ y ago20:16

20:16

On today’s episode, Dr Nicolas Rivron, group leader at the Institute of Molecular Biotechnology, Austrian Academy of Science, is interviewed by PhD student Sergi Junyent Espinosa. Nicolas discusses his research building stem-cell based embryo models. He talks about the self-organising nature of tissue development in the embryo and how this can help…

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Episode 131 - Vivian Li - “I felt like the intestine is actually quite a beautiful system.” 18:38

3+ y ago18:38

18:38

On today’s episode, Dr Vivian Li, group leader of the Stem Cell and Cancer Laboratory at the Francis Crick Institute, is interviewed by PhD student Elena Drudi. Vivian talks about her background in plant biotechnology, colon cancer research and working in Hans Clevers lab and her current research focus using human gut organoids to ask how stem cell…

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Episode 130 - Derk Ten Berge - "It does require some bravery to spend the time to look for that" 16:58

3+ y ago16:58

16:58

In today’s episode, Dr Derk ten Berge, an Associate Professor in the department of Cell Biology at Erasmus MC University Medical Center Rotterdam, is interviewed by PhD student Daria Belokhvostova. Derk discusses his research on embryonic development and pluritpotency (the ability of a stem cell to make all the cells of the embryo) and the mechanis…

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Episode 129 - Ana-Maria Cujba - "I think my passion is for organoids." 14:16

4y ago14:16

14:16

Ana-Maria Cujba, a PhD student at the Centre for Stem Cell's and Regenerative Medicine at King's College London, is interviewed by PhD student Ella Hubber. Ana-Maria discusses her work using human induced pluripotent stem cells and pancreatic organoids to study a new mechanism in mature onset diabetes of the young (MODY). She dives into the develop…

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Episode 128 - Prof Muzlifah Haniffa - "We are going to map the 37 trillion cells in the human body." 12:56

4y ago12:56

12:56

Professor Muzlifah Haniffa, Professor of Dermatology and Immunology at Newcastle University, is interviewed by researcher Dr Clarisse Ganier. Muzz talks about her pioneering work in the fields of dermatology, immunology and genomics. She discusses her involvement in the human cell atlas, that aims to map all the cells of the human body. Muzz also s…

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Episode 127- Prof Francesco Saverio Tedesco - “Seeing patients gives you the right motivation.” 15:48

4y ago15:48

15:48

Prof Francesco Saverio Tedesco, Professor of Neuromuscular Biology and Regenerative Medicine at University College London, is interviewed by researcher Dr Davide Danovi. Francesco talks about his work using stem cells to understand and develop new therapies for muscular diseases such as muscular dystrophy. He speaks about the balance between his pr…

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Episode 126 - Dr Madeline Lancaster - "It was a classic story of scientific serendipity" 12:48

4y ago12:48

12:48

Dr Madeline Lancaster, Group Leader at the Cell Biology Division of the MRC Laboratory of Molecular Biology in Cambridge, is interviewed by PhD student Ella Hubber. Madeline talks about the chance discovery and ongoing development of cerebral organoids and their use in studying human brain development and size differences between human and non-huma…

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Episode 125 - Dr Jürgen Knoblich- “Studying the brain is like studying oneself.” 20:57

4y ago20:57

20:57

On today’s episode, Dr Jürgen Knoblich, scientific director at the Institute of Molecular Biology at the Austrian Academy of Sciences, is interviewd by PhD student Sergi Junyen. Jürgen talks about his research journey to studying brains, the benefits of using fruit flies (Drosophila) in research, and the development and future of cerebral organoids…

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Episode 125 - Dr Randolph Ashton - "I have faith in the cells, they can do a lot themselves." 11:53

4y ago11:53

11:53

Randolph Ashton, Associate Professor of Biomedical Engineering at University of Wisconsin-Madison, is interviewed by PhD student Ieva Berzanskyte. Randolph discusses his research engineering novel materials and methodologies to direct stem cell behaviour in a reproducible and scalable manner. He talks about how harnessing the natural ability of cel…

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Episode 124 - Prof Weiss - "When I realised we could programme cells, I knew it is what I had to do" 22:41

4y ago22:41

22:41

Today Ron Weiss, Professor in the Department of Biological Engineering and in the Department of Electrical Engineering and Computer Science at the Massachusetts Institute of Technology and Director of the Synthetic Biology Center at MIT, is interviewed by PhD student Matt Chung. Ron is a pioneer in the field of synthetic biology, using computer eng…

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Episode 123 - Prof Manuel Serrano - "Understanding aging can help treat other diseases." 14:04

4y ago14:04

14:04

Today, Professor Manuel Serrano from the Institute for Research in Biomedicine in Barcelona is interviewed by PhD student Emily Read. Manuel has produced seminal work in the fields of tumour suppression, senescence, ageing and reprogramming. In this episode he talks about the link between senescence and regeneration, and how this can become disrupt…

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Episode 122- Prof Matthias Lütolf - "Organoids give us a new window into human biology." 23:33

4y ago23:33

23:33

Today, Professor Matthias Lütolf, Head of the Laboratory of Stem Cell Bioengineering at The École polytechnique fédérale de Lausanne is interviewed by PhD student Emily Read. Matthais talks about how scientists can begin to build human diseases in a dish using organoid technologies. He discusses the importance of understanding how physical factors …

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Episode 121 - Prof Kevin Eggan - "Science progresses through replication, validation, extension" 15:52

4y ago15:52

15:52

Today, Professor Kevin Eggan from the Department of Stem Cell and Regenerative Biology at Harvard University, is interviewed by PhD student Peter Harley. Kevin talks about the difficulties of studying neurodegenerative disorders and applying stem cell technologies to study motor neuron disease/ALS. He discusses why highlighting and understanding co…

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Episode 120 - Prof Salvador Benitah - "I still have to sit down and learn new things" 23:33

4y ago23:33

23:33

Prof Salvador Aznar Benitah, ICREA Research Professor at Institut de Recerca Biomèdica, is interviewed by PhD student Victoria Tsang. Salvador talks about his research understanding the molecular pathways that dictate stem cell behaviour, including his recent work on the role of dietary fats, and how this goes wrong in cancer. He talks about recent…

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Episode 119 - Prof Alfonso Martinez Arias - "The 21st Century is the Century of the Cell." 20:11

4y ago20:11

20:11

Professor Alfonso Martinez Arias, professor of developmental mechanics in the department of genetics at the University of Cambridge, is interviewed by PhD student Alice Vickers. Alfonso discusses the applications, ethical considerations, legislation, and difficulties of progressing his research using embryonic stem cells as a model system for study…

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Episode 118 - Prof Trepat - "The biggest questions of our generation are in life sciences" 13:23

4y ago13:23

13:23

Professor Xavier Trepat, ICREA Research Professor at Institut de Bioenginyeria de Catalunya, is interviewed by PhD student Sebastiaan Zijl. Xavier talks about his work understanding how physical forces impact how cells grow, move and behave. He discusses the coolest experiment he has ever done and how lockdown has unexpectedly benefited his lab.For…

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Episode 117 - Prof Peter Zandstra - "We are bringing technology and biology together" 12:57

4y ago12:57

12:57

Professor Peter Zandstra, Director of the Michael Smith Laboratories at The University of British Columbia, is interviewed by Group Leader Dr Davide Danovi. Peter talks about his work understanding blood development from stem cells and how this can be used improve therapeutics for diseases such as leukaemia. He discusses his beginnings as a chemica…

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Episode 116 - Dr William Grey - Are proteins the key to understanding cancer? 12:21

4y ago12:21

12:21

Dr William Grey, a post doctoral researcher in the Haematopoietic Stem Cell Laboratory at the Francis Crick Institute, is interviewed by PhD student Jana Obajdin. William talks about using umbilical cord blood in the treatment of genetic disorders and the future of cancer therapies. He also tells us why the study of proteins is an exciting and expa…

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Episode 115 - Prof James Briscoe - Where does time come from in development? 7:30

4+ y ago7:30

7:30

Prof James Briscoe, group leader of the Developmental Dynamics Lab at the Francis Crick Institute, is interviewed by PhD student Ieva Berzanskyte. James talks about his research into the developing spinal cord and thinks about what is currently fascinating him, including understanding the "tempo" of embryonic development.For more information on Jam…

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Episode 114 - Prof Janet Rossant - "Science is going to get us out of this, science is the answer." 16:25

4+ y ago16:25

16:25

Prof Janet Rossant, Senior Scientist on the Developmental & Stem Cell Biology Program, Chief of Research Emeritus at the SickKids Research Institute, President and Scientific Director of the Gairdner Foundation and Professor in the Departments of Molecular Genetics and Obstetrics & Gynaecology at the University of Toronto, is interviewed by PhD stu…

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Episode 113 - Prof Olivier Pourquié - "I think pretty much every bit of Biology is interesting." 13:48

4+ y ago13:48

13:48

"It’s a mindset."Prof Olivier Pourquié, Professor of Pathology and Professor in the Department of Genetics at Harvard Medical School, is interviewed by PhD student Ella Hubber. Olivier breaks down how spinal vertebrae are formed in the embryo through a “segmentation clock” and how understanding this is relevant to human disease. He also talks about…

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Episode 112 - Prof Cristina Lo Celso - "At the time stem cells seemed like the holy grail." 11:41

4+ y ago11:41

11:41

Prof Cristina Lo Celso, Professor of Stem Cell Biology and group leader at Imperial College London, is interviewed by PhD student Elena Drudi. Cristina discusses her work visualising blood stem cells and determining the factors that control their function, to better understand mechanisms underlying blood based cancers. She also talks about her care…

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Episode 111 - Dr Ivo Lieberam - "How we are going to interact with technology in the long term?" 17:16

4+ y ago17:16

17:16

We return this week to an episode recorded during lockdown.Dr Ivo Lieberam, Senior Lecturer and group leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Eva Hamrud. Ivo discusses his work on generating neuromuscular models in a dish that can be used to understand neuromuscular disea…

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Episode 110 - Dr Francesca Spagnoli- "We study biological problems with direct medical application." 12:59

4+ y ago12:59

12:59

We return this week with an episode recorded during lockdown. Dr Francesca Spagnoli, Group Leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Teodora Manea. Francesca discusses her group's research on understanding how pancreatic beta cells communicate with their environment and the…

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Episode 109 - Prof James Sharpe - "You were limited by nothing but your own imagination." 13:22

4+ y ago13:22

13:22

We return this week with an episode recorded during lockdown.Prof. James Sharpe, the head of EMBL Barcelona, is interviewed by PhD student Sergi Junyent. Prof. Sharpe is one of the key opinion leaders in developmental biology and bioengineering. Here, he talks about the pioneering work done by his group in understanding tissue development and discu…

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Episode 108 - Prof Jianping Fu - “Human development itself is just fascinating.” 18:06

4+ y ago18:06

18:06

“Even just to understand the genesis of human being itself... It must be one of the holy grails of modern biology.”We return this week with an episode recorded during lockdown. Professor Jianping Fu, a professor of Mechanical Engineering, Biomedical engineering and Cell and Developmental Biology at the University of Michigan, is interviewed by PhD …

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Episode 107 - Prof Ludovic Vallier - "The drive is to generate more knowledge." 17:41

4+ y ago17:41

17:41

We return this week with an episode recorded during lockdown.Professor Ludovic Vallier, Professor of Regenerative Medicine within the Department of Surgery at Cambridge University and director of the National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre hIPSCs (human induced pluripotent stem cells) core facility, is int…

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Episode 106 - Professor Peter Jones - "I think all scientists are curious by nature." 11:21

4+ y ago11:21

11:21

We return this week with an episode recorded during lockdown.Professor Peter Jones, Professor of Endocrine Biology and head of the Department of Physiology at King's College London, is interviewed by PhD student Prudence Lui. Peter breaks down the basics of type 1 and type 2 diabetes and discusses his lab's recent research into the phenomenon of mi…

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Episode 105-Dr Norah Fogarty-"Understanding the placenta we may treat disease before manifestation" 12:24

4+ y ago12:24

12:24

We return this week to an episode recorded during lockdown.Dr Norah Fogarty, a new group leader at the Centre for Stem Cells and Regenerative Medicine at King's College London, is interviewed by PhD student Geraldine Jowett. Norah discusses her work on the development of the trophectoderm in the human embryo, which is the progenitor of early placen…

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