Τα καλύτερα Precision Medicine podcast (2024)

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The Science and Art of De-risking Cancer Drug Development | Talking Precision Medicine #35 31:27

7d ago31:27

31:27

In this episode Genialis CEO Rafael Rosengarten sat down with Dr. Carolina Haefliger, head of translational medicine at Debiopharm, the privately held Swiss biopharma company focused on oncology drug development. They talked about de-risking promising new cancer drugs, and what it takes from the science to the team to the technologies. Episode 35 l…

1
From Access to AI: Cancer in America with Dr. Douglas Flora 36:04

24d ago36:04

36:04

In this episode of the Precision Medicine Podcast, host Karan Cushman does some time traveling with Dr. Douglas Flora through his lifetime journey with cancer. Dr. Flora is the Medical Director of Oncology Services at St. Elizabeth Healthcare and Editor-in-Chief AI in Precision Oncology, a peer-reviewed research journal dedicated to advancing artif…

1
Professional grade software — a key ingredient in cutting edge biomedical discovery | Talking Precision Medicine #34 31:38

4M ago31:38

31:38

Today we turn the mic around, as our guest Adam Stasio hosts an excellent podcast of his own. Adam’s day job, however, is running SciMed, a boutique life sciences software development company. Adam and Genialis CEO Rafael Rosengarten discuss the state of scientific software, the importance of agility and communication, and approaches to building a …

1
New Medicines from Evolutionary Pathways: Using Comparative Genomics to Treat Human Disease | Talking Precision Medicine #33 42:45

6M ago42:45

42:45

Our guest today is Dr. Ashley Zehnder, co-founder and CEO of Fauna Bio. Fauna is a revolutionary young biotech company using comparative genomics of an array of non-traditional mammalian models to discover new therapeutic opportunities for people. What do ground squirrels have to do with treating battlefield trauma? Only one way to find out … Visit…

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To achieve personalized medicine, start by getting the dose right | Talking Precision Medicine #32 39:13

9M ago39:13

39:13

In this episode, Genialis CEO Rafael Rosengarten sits down with Ajay Gopal, CEO and founder of Rx Studio. Rx Studio is a technology company using data science to tackle a major limitation to personalized medicine: drug dosing. Visit TPM E32 for highlights and links from this episode.

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Xenotransplantation and Regenerative Medicine 30:14

9M ago30:14

30:14

What if we could replace diseased or damaged organs and other body parts with new lab-created versions? How might transplanting tissue from other species help the critical shortage of human transplant organs? Tune in to listen to two noted experts in regenerative therapeutics and xenotransplantation (transplanting organs between members of differen…

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AI and Ethics in Healthtech: Who is Innovating Most? | Talking Precision Medicine #31 34:41

10M ago34:41

34:41

In this episode, Genialis CEO Rafael Rosengarten speaks with BCG management consultant and healthcare innovation expert Amy MacDougall. They discuss emerging trends in healthcare, the role of AI, ethics and more, as well as BCG’s recently released 50 Most Innovative Companies List. Visit TPM E31 for highlights and links from this episode.…

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Wearables and Digital Health 35:34

10M ago35:34

35:34

Wearable technology has come a long way from being a novelty. These wearables are now being used to help monitor patients to forestall problems. They can help people take a more active role in their health. Plus, the trove of data they collect can help medical researchers. Explore how wearables and digital health individualize medicine in this epis…

1
Digital Health Enabled Genomics 36:31

10M ago36:31

36:31

Wearable technologies are becoming more and more popular. Add to the mix digital health apps and there's a trove of data being translated into meaningful health information for users, physicians and researchers. Explore the emergence of these digital tools in individualized medicine in this episode of Mayo Clinic's "The Pursuit of Precision: The Sc…

1
People first: building a company that inspires impactful work | Talking Precision Medicine #30 51:06

11M ago51:06

51:06

This episode, Genialis’ thirtieth, is a bit different from the previous ones. CEO Rafael Rosengarten has not one, not two, but three guests, including the entire leadership team at Genialis. The gang discusses Genialis’ twin quests to build a great place to work and a business that makes a positive impact on the world. Visit TPM E30 for highlights …

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Organoids: A Powerful Tool for Individualized Medicine Research 21:15

11M ago21:15

21:15

Organoids are like mini organs giving researchers new insights into human development and disease and could revolutionize fields like drug discovery. Researchers can develop a wide variety of organoids from the liver to the brain. Hear about the potential and limitations of using human organoids to bridge the gap between human and animal research. …

1
Clinical Trial Design for Individualized Medicine 36:53

11M ago36:53

36:53

Dive into how some of the changes in clinical trials can be applied to the stages of the cancer continuum, including cancer prevention, early detection and treatment. Listen to two noted experts discuss how individualized medicine has changed the clinical trials field. Find out more about the next generation of clinical trials researchers are using…

1
3D Tissue Models in Healthcare 44:47

11M ago44:47

44:47

Find out how 3D printing techniques play a key role in developing tissues that could be implanted into humans. Two noted experts in the field of 3D printing in medicine discuss the technological advancements, in-house printing, reimbursement challenges and applications in surgery to improve patient care. Guests are: Jonathan Morris, M.D., Associate…

1
Dr. Pranil Chandra and Dr. Luis Raez: Enabling Comprehensive Genomic Profiling in Lung Cancer 46:13

12M ago46:13

46:13

In this episode of the Precision Medicine Podcast, hosts Karan Cushman and Clynt Taylor welcome back Dr. Luis Raez, Medical Director and Chief Scientific Officer at Memorial Cancer Institute who is joined by Dr. Pranil Chandra, Chief Genomic Officer at PathGroup. Together, we discuss the key barriers to performing comprehensive genomic profiling in…

1
Individualized Vaccines for Cancer 28:28

12M ago28:28

28:28

Some vaccines prevent cancer, while other vaccines treat cancer. Listen to two noted experts in immunology as they discuss the differences between the two vaccines, the excitement and challenges in the precision oncology world on how to design vaccines for individual cancer types, the importance of clinical trials, and advances in immunotherapy. Gu…

1
Rapid Genome Sequencing 29:28

1y ago29:28

29:28

Mayo Clinic offers a rapid genome sequencing test for newborns where they sequence the entire genome of the baby and compare it to the parent’s DNA to identify the causes of severely ill newborn babies. Find out more about this new field of genomic medicine, ethics involved and the potential and hurdles of using genome based newborn screening as st…

1
Molecular Virology and Novel Therapeutics for Individualized Medicine 27:34

1y ago27:34

27:34

What are the challenges of dealing with viruses like COVID-19? Two infectious disease experts discuss lessons learned in the pandemic, vaccines, and novel therapeutics. Some viruses are easier to defeat with a vaccine and others are not. Learn about new technology to attack emerging viruses, the importance of funding to develop drugs and how resear…

1
Population Genomics 31:01

1y ago31:01

31:01

Did you know that any two human beings are 99.9% identical? Learn more from two experts in population genomics, the large-scale comparison of DNA sequences of populations and how groups are related over time. Understand the drivers of disease and how genetics affects our risks across the population. Discover how researchers are moving population ge…

1
Exposomics and Health Risk Assessment 32:59

1y ago32:59

32:59

In the inaugural podcast episode host Cathy Wurzer, a broadcast journalist from Minnesota Public Radio, talks with two experts in this new frontier of medicine. The exposome looks at everything a person has been exposed to in their lifetime — chemicals, pollution, radiation, biological agents, nutrients in food and measures those exposures to ident…

1
Communication, the key to building community | Talking Precision Medicine #29 44:54

1y ago44:54

44:54

Our guest this episode is Dr. Susanna Harris, community lead at Vibe Bio. Susanna is a dedicated scientific communicator and an outspoken advocate for the mental health of PhD students and other science researchers. She has chronicled her journey from the academic lab bench to a venture incubator to a promising biotech company for a substantial soc…

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Dr. Debra Patt: Texas Oncology Has an “Easy Button” for Delivering Consistent Precision Oncology Care 26:37

1+ y ago26:37

26:37

To mark the beginning of Season 5 of the Precision Medicine Podcast, we are honored to welcome Dr. Debra Patt, Executive Vice President of Texas Oncology. As an oncologist and breast cancer specialist at one of the nation’s largest community cancer practices, Dr. Patt is on the frontlines of oncology care every day. She joins us to discuss how Texa…

1
A new way to finance drug development, for rare disease and beyond | Talking Precision Medicine #28 45:36

1+ y ago45:36

45:36

In this episode, our host and Genialis CEO Rafael Rosengarten spotlights Vibe Bio. Vibe Bio is a new biotech aiming to disrupt how we finance drug development through stakeholder communities and cryptocurrency, starting in the rare disease arena. Our guest is Alok Tayi, co-founder and CEO of Vibe. Alok is a successful serial entrepreneur and a rare…

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What’s in a Name?: Endpoint Health’s Patient-Centric Northstar | Talking Precision Medicine #27 43:16

2y ago43:16

43:16

This episode features Jason Springs, co-founder and CEO of Endpoint Health, an ascendant precision therapeutics company. Jason is a serial entrepreneur, who with the co-founders of his previous company, is building Endpoint Health to bring together under one roof the data science, diagnostics and therapeutics necessary to achieve truly personalized…

1
Do We Have the Will to Address Inequality in Precision Oncology? A Conversation with Dr. Karen Winkfield 52:41

2y ago52:41

52:41

In this episode, we are joined by Dr. Karen Winkfield, Executive Director of the Meharry-Vanderbilt Alliance, appointee to President Joe Biden's National Cancer Advisory Board, and co-host of the weekly podcast, 3 Black Docs, which is dedicated to educating the community about health and health disparities in an approachable and entertaining way. D…

1
Dr. Stephen Kingsmore on Scaling Whole Genome Sequencing for Uncovering Genetic Defects in Infants 38:20

2y ago38:20

38:20

In episode 55 of the Precision Medicine Podcast, we welcome Dr. Stephen Kingsmore, President and CEO of the Rady Children's Institute for Genomic Medicine. Dr. Kingsmore joins us to discuss the extraordinary role whole genome sequencing is playing in prolonging and improving the life of critically ill newborns. Read the full summary and tune in her…

1
Taking charge of your health future with wearables and AI | Talking Precision Medicine #26 33:33

2y ago33:33

33:33

In this episode 26, our host Rafael sits down with Harry Glorikian. Harry is an investor, author, podcaster and veteran of the healthtech industry. Harry walks us through his latest book, The Future You, and expounds on the ways that wearable devices, personal health data and artificial intelligence are changing healthcare as we know it. Visit TPM …

1
Leading Thoracic Oncologist, Dr. Christian Rolfo, Explains How Liquid Biopsies Are Advancing Precision Medicine 30:49

2y ago30:49

30:49

Dr. Christian Rolfo, President of the International Society of Liquid Biopsy and Associate Director for Clinical Research at the Center of Thoracic Oncology at the Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai in New York City, joins us to explain the unique role liquid biopsies are playing in the diagnosis and treatment of …

1
LUNGevity Leaders Discuss Their Commitment to Educating Lung Cancer Patients About the Importance of Biomarker Testing 40:13

2+ y ago40:13

40:13

In this Precision Medicine Podcast episode, we are joined by Dr. Belinda King-Kallimanis, Director of Patient-Focused Research at LUNGevity—an organization that brings together research, education and support services for patients and caregivers in the lung cancer community—and Nichelle Stigger, LUNGevity board member and lung cancer survivor. They…

1
Then and Now: The Progress of Precision Medicine Diagnostics with Hannah Mamuszka and Lena Chaihorsky of Alva10 34:53

2+ y ago34:53

34:53

In celebration of the three-year anniversary of the Precision Medicine Podcast, we take a look back at how far precision diagnostics have come with the help of one of our first guests Hannah Mamuszka, Founder and CEO of Alva10, and her colleague Lena Chaihorsky. Both women are focused on resolving the knowledge gap between payers and diagnostic com…

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Author and Breast Cancer “Previvor” Ali Rogan on How Progress in Precision Medicine Empowers Patients to Make Informed Decisions 40:01

2+ y ago40:01

40:01

In this episode, in honor of Breast Cancer Awareness Month, we speak with Ali Rogin, author of Beat Breast Cancer Like a Boss and award-winning producer of PBS NewsHour. Ali is what is commonly known as a breast cancer previvor, someone who knows they have a mutation that may lead to cancer and takes preventative steps to avoid a diagnosis. With th…

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Real-Time Multiplexed Biomarkers: The Next Generation of Continuous Monitoring | Talking Precision Medicine #25 31:47

2+ y ago31:47

31:47

Earlier this summer, Rafael sat down with Peter Vranes and Hitesh Mehta, co-founders of Nutromics. Nutromics is developing a next generation lab-on-skin, a wearable device for continuous monitoring of health-critical biomarkers. Let’s get right to it. Visit TPM 25 for highlights and links from this episode.…

1
Dr. Kashyap Patel Tackles Oncology Treatment Disparities and Brings Light to the Darkest Areas of Cancer Care 39:32

2+ y ago39:32

39:32

For our 50th episode, we welcome Dr. Kashyap Patel, medical oncologist and CEO of Carolina Blood and Cancer Center, current president of the Community Oncology Alliance (COA), and author of the book, Between Life and Death: From Despair to Hope. Dr. Patel explains the social determinants that can impact the quality of care and opportunity for preci…

1
Fostering Patient Journeys Around the World | Talking Precision Medicine #24 40:42

2+ y ago40:42

40:42

Our guest is Dr. Angeli Moeller, Head of Pharma International Informatics at Roche. Angeli and our host, Rafael, discuss data science in the big pharma leagues; geek out on data standards; and dive deep on patient data rights and barriers to care. Visit TPM E24 for highlights and links from this episode.…

1
Janine Morales, PhD On Applying Precision Medicine More Strategically With Molecular Testing 32:21

2+ y ago32:21

32:21

In this episode of the Precision Medicine Podcast, Janine Morales, PhD, Chief Scientific Officer at Trapelo Health takes us inside the complex world of evidence-based decision making in oncology. Specifically, she dives deeps into some of the nuances in the latest targeted therapy approvals and explains how having access to a real-time knowledge-ba…

1
Dr. Howard McLeod on Chasing the Fun and the Power of Collaboration in Precision Medicine 40:36

3y ago40:36

40:36

Dr. Howard McLeod is Medical Director for Precision Medicine at The Geriatric Oncology Consortium, a fellow of the American Society of Clinical Oncology and has worked on research projects with some of the most notable institutions around the world, including FDA, NIH, and NCI. We cover a lot of ground with Dr. McLeod in this podcast, including car…

1
Bill Bonello and Clynt Taylor Examine the Future of Precision Medicine and How to Provide Better Access to More Patients 29:17

3y ago29:17

29:17

Bill Bonello, president of NeoGenomics Informatics, and Clynt Taylor, president of Trapelo Health, discuss challenges in precision medicine and how evidence-based technologies can help deliver more appropriate, value-based care to more patients. As a subtext to the discussion is the recent acquisition of Trapelo Health, creator of clinical decision…

1
Dr. Caroline Carney and Clynt Taylor Discuss Managing the Total Cost of Care in Precision Medicine 32:22

3y ago32:22

32:22

In this notable episode, Dr. Caroline Carney, Chief Medical Officer at Magellan Health, and Clynt Taylor, CEO at Trapelo Health, join us to discuss how collaborative technologies can help payers more effectively manage the cost of precision oncology while delivering the best outcomes for patients. Read the full summary.…

1
Dr. F. Anthony Greco Explains How Precision Medicine Has Led to Better Treatments for Cancers of Unknown Origins 33:29

3y ago33:29

33:29

In this episode, Dr. F. Anthony Greco, medical oncologist at Tennessee Oncology, discusses the role that precision medicine has played in improving our diagnosis and treatment of cancer.Από τον Trapelo

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From Cancer to Covid, Drug Intelligent Science at Breakneck Pace | Talking Precision Medicine #23 47:19

3y ago47:19

47:19

Our guest for this episode of Talking Precision Medicine is Liang Schweizer from HiFiBiO Therapeutics - one of the most exciting young biotechs out there. They have built a discovery engine encompassing single cell, immune profiling and machine learning. Visit TPM E23 for highlights and links from this episode.…

1
Dr. Gabriel Bien-Willner Part 2: Helping Payers Adapt to the Paradigm Shift of Precision Medicine 25:28

3y ago25:28

25:28

In this Part 2 podcast featuring Dr. Gabriel A. Bien-Willner, Medical Director of the MolDX programat Palmetto GBA, we dive into the core challenges that payers face in navigating the explosion of precision medicine tests and treatments, and specifically how the prior authorization process can be streamlined by keeping payers updated on changes in …

1
AbbVie’s Christopher Boone Integrates Real-World Data with Precision Medicine for Better Patient Outcomes 36:14

3y ago36:14

36:14

Christopher Boone, Vice President and Global Head of Health Economics & Outcomes Research at AbbVie, shares his thoughts on how using data to understand a patient’s real-world environment can expand the practice of Precision Medicine.Από τον Trapelo

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Precision Medicine is Coming Faster Than You Think: Guests Rob Metcalf and Clynt Taylor 26:30

3+ y ago26:30

26:30

It is fitting that our first guests on Season 3 of the Precision Medicine Podcast are Rob Metcalf, CEO of Concert Genetics and Clynt Taylor, CEO of Trapelo Health who are both innovators in precision medicine technology. What we learn from them in this episode is that after 20 years of hearing about the “promise of precision medicine,” technology h…

1
Dr. Luis Raez Discusses the Impact of Precision Medicine in Lung Cancer Treatment 35:37

3+ y ago35:37

35:37

In this episode, and in honor of lung cancer awareness month we had the opportunity to speak with Dr. Luis Raez, Medical Director and Chief of Hematology Oncology at Memorial Cancer Institute who focuses on treating lung cancer. Hear how the emergence of next-generation sequencing has changed his approach to lung cancer treatment, what notable disc…

1
Ethics and Policies of Precision Medicine on the Global Stage | Talking Precision Medicine #22 49:32

3+ y ago49:32

49:32

Our guests for this episode of Talking Precision Medicine are Elissa Prichep and Cameron Fox of the World Economic Forum. Elissa and Cameron take us through the W.E.F’s precision medicine initiative, and explain how anticipating ethical tensions is key to envisioning policies for precision medicine across the globe. Visit TPM E22 for highlights and…

1
Dr. Gabriel Bien-Willner Part 1: Reshaping Reimbursement Policies for Genetic and Genomic Testing 20:36

3+ y ago20:36

20:36

In the first of a two-part podcast, Gabriel A. Bien-Willner MD, PhD, FCAP, Medical Director at MolDX, and Chief Medical Officer at Palmetto GBA shares how he has helped implement payer controls and coverage and set policies for affiliated Medicare Administrative Contractors in 28 states. In the past, payers have had to navigate the growing field of…

1
Breast Cancer Specialist Dr. Mark Moasser Discusses Overcoming Barriers to Clinical Trial Access 24:26

3+ y ago24:26

24:26

Dr. Mark Moasser, a physician-scientist and breast cancer specialist at the University of California, San Francisco discusses his research focus on the HER2 oncogene, the latest trial findings and the importance of improving patient access to clinical trials. At Trapelo, connecting oncologists with patient-appropriate clinical trials is a major par…

1
Rebooting generics to fight cancer | Talking Precision Medicine #21 51:12

3+ y ago51:12

51:12

Reboot Rx is a different kind of biotech startup. Reboot’s mission is to find generic non-cancer drugs that can benefit cancer patients quickly and affordably. And as a not-for-profit, Reboot can stay focused on its mission. Given the number of paradigms Reboot hopes to shift at once, we decided to talk with all three co-founders: CEO Laura Kleiman…

1
Lori Brisbin Explains How Trapelo Helps Keep Texas Oncology Ahead of the Precision Medicine Curve 15:42

3+ y ago15:42

15:42

In this episode, Clynt Taylor, CEO at Trapelo Health, talks with Lori Brisbin, Vice President of Precision Medicine at Texas Oncology, one of the largest practices in the United States. The discussion centers on how this expansive network of oncologists is leveraging the web-based Trapelo™ platform to provide evidence-based decision support to its …

1
Robin Toft on the Life Science Industry’s Talent Crisis, Advancement for Women, and Why It’s Critical for CEO’s to Focus on Diversity 19:24

4y ago19:24

19:24

On this Precision Medicine Podcast, author and CEO of the Toft Group (a ZRG company), Robin Toft, joins us to discuss her new book, We Can, and share her thoughts on the need for more women and greater diversity in the C-suite and the boardroom within the life science industry. Read the full summary here.…

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Stopping sepsis in its tracks… oh, and COVID19 too! | Talking Precision Medicine #20 46:55

4y ago46:55

46:55

Today Rafael is joined by Dr. Sarma Velamuri, founder and CEO of Luminare. Luminare is a Houston-based digital health company dedicated to ending sepsis—the number 1 cause of death in US hospitals. In the conversation that follows, Dr. Velamuri explains how Luminare saves lives by streamlining hospital workflows, and by changing the behaviors of nu…

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