Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
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Insightful conversations with leading experts in the field of health care, medical research, policy, and more from the New England Journal of Medicine (NEJM). Each episode examines the many complexities found at the junction of medicine and society.
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Audio podcasts featuring the week’s top medical news plus pertinent interviews
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The House reflects medicine’s most pressing issues through the eyes of residents, providing a forum to share their stories from the bedside, where they are learning far more than the lessons of clinical medicine.
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A Day in the Life is a podcast for medical students, by medical students. Interviews with attendings about daily life and training may help you explore a range of specialties.
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NEJM Interview: I. Glenn Cohen on the professional implications of the use of artificial-intelligence–based monitoring systems in medicine.
7:17
I. Glenn Cohen is a professor of law and deputy dean at Harvard Law School and faculty director of the Petrie-Flom Center for Health Law Policy, Biotechnology, and Bioethics at Harvard University. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. I.G. Cohen, I. Ajunwa, and R.B. Parikh. Medical AI and Clinician Sur…
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Featuring articles on mismatch repair–deficient tumors, generalized myasthenia gravis, HER2-mutant non–small-cell lung cancer, a Corynebacterium diphtheriae outbreak, and hereditary and sporadic papillary kidney cancer; a review article on unruptured intracranial aneurysms; a case report of a man with respiratory failure and shock after kidney tran…
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NEJM Interview: Amanda Kallen on the history of women’s health research and recent actions that are jeopardizing progress in women’s health.
12:45
Amanda Kallen is an associate professor in the Division of Reproductive Endocrinology and Infertility at the University of Vermont Larner College of Medicine and an adjunct professor at the Yale School of Medicine. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.N. Kallen and Others. Undermining Women’s Health…
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Featuring articles on treatments for pulmonary fibrosis, for obesity and overweight, for severe hemophilia B, and for a rare genetic disease; a review article on malnutrition in older adults; a case report of a man with a nasopharyngeal mass; a Medicine and Society on John Collins Warren; and Perspectives on undermining women’s health research, on …
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NEJM Interview: David Jones on the disparate historical approaches to anemia diagnosis and their lessons for physicians.
40:04
Watch the NEJM In Studio video of this interview at NEJM.org. David Jones is the Ackerman Professor of the Culture of Medicine at Harvard University. Harleen Marwah, the interviewer, is an Editorial Fellow at the Journal. W. Xue and D.S. Jones. Debating Race and the Diagnosis of Anemia — How Medicine Moved Away from Race-Based Standards. N Engl J M…
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Amar Kelkar is a physician at the Dana-Farber Cancer Institute and an instructor in medicine at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.H. Kelkar. U.S. Research Leadership at a Crossroads — The Impact of Reducing NIH Indirect-Cost Coverage. N Engl J Med 2025;392:2081-2084.…
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Featuring articles on metabolic dysfunction–associated steatohepatitis, lung nodules, breast cancer, and improving birth outcomes; a review article on hemoglobinopathies; a Clinical Problem-Solving on from where it stems; and Perspectives on U.S. research leadership at a crossroads, on health care in an evolving immigration landscape, and on carryi…
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NEJM Interview: Zirui Song on the rise of concierge and direct primary care practices in the United States.
13:12
Zirui Song is an associate professor of health care policy and medicine at Harvard Medical School and a general internist at Massachusetts General Hospital. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. Z. Song and J.M. Zhu. Primary Care — From Common Good to Free-Market Commodity. N Engl J Med 2025;392:1977-1…
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Featuring articles on pulmonary arterial hypertension, oral semaglutide and cardiovascular outcomes, giant-cell arteritis, the loss of subsidized drug coverage and mortality, and neutralizing venom toxins; a review article on cancer of unknown primary site; a case report of a man with fever, nausea, and respiratory failure; and Perspectives on prim…
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NEJM Interview: Alice Chen on responding to the U.S. administration’s threats to health and physicians’ values and maintaining hope in difficult times.
11:14
Alice Chen is a primary care internist in Washington, DC, and former executive director of Doctors for America. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.T. Chen and V.H. Murthy. The Power of Physicians in Dangerous Times. N Engl J Med 2025;392:1873-1875.
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Featuring articles on multiple sclerosis, narcolepsy type 1, antiretroviral therapy in children with HIV, and porcine kidney xenotransplantation; a review article on Ph-positive acute lymphoblastic leukemia; a case report of a woman with peritonsillar swelling and bleeding; and Perspectives on the power of physicians in dangerous times, on communit…
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NEJM Interview: Christopher Duggan on the effects of ending U.S. foreign-assistance and global health programs.
7:06
Christopher Duggan is the director of the Center for Nutrition at Boston Children’s Hospital, a professor of pediatrics at Harvard Medical School, and a professor in the Departments of Nutrition and Global Health and Population at the Harvard T.H. Chan School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of …
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Featuring articles on high-risk smoldering multiple myeloma, M. tuberculosis infection, type 2 diabetes, uncontrolled hypertension, and lymphoma; a review article on the chemistry of food; a case report of a man with weight loss, weakness, and anorexia; and Perspectives on the dismantling of foreign-assistance efforts, on the crushing weight of non…
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NEJM Interview: Arthur Robin Williams on alcohol consumption in the United States and the effects of alcohol taxes.
9:26
Arthur Robin Williams is an associate professor of clinical psychiatry at Columbia University and a research scientist at the New York State Psychiatric Institute. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. A.R. Williams. Death and Taxes — Is Alcohol the Solution? N Engl J Med 2025;392:1665-1667.…
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Featuring articles on lipoprotein(a), familial polycythemia, leukocyte adhesion deficiency, COPD, and on policies on reducing alcohol consumption; a review article on addressing alcohol use; a Clinical Problem-Solving on gazing into a crystal ball; and Perspectives on death and taxes, on cancer metastases, and on a good innings.…
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NEJM Interview: Lauren Jatt on the efficacy of twice-yearly lenacapavir for preexposure prophylaxis and its implications for the development of an HIV vaccine.
8:23
Lauren Jatt is an infectious diseases fellow at the University of Washington. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. L.P. Jatt and Others. An HIV Vaccine in the Era of Twice-Yearly Lenacapavir for PrEP — Essential or Irrelevant? N Engl J Med 2025;392:1561-1563.…
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Featuring articles on bronchiectasis, influenza, clonal hematopoiesis of indeterminate potential, and metachromatic leukodystrophy; a review article on biology of the Fc neonatal receptor; a case report of a woman with sore throat and rash; and Perspectives on HIV preexposure prophylaxis, on fossil fuels, and on Medicaid’s mandate for children and …
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In this NEJM Outbreaks Update, Editor-in-Chief Eric Rubin and Deputy Editor Lindsey Baden are joined by Indiana Commissioner of Public Health Lindsay Weaver to discuss the current state of avian influenza in Indiana. Eric Rubin is the Editor-in-Chief of the Journal. Lindsey Baden is a Deputy Editor of the Journal. Lindsay Weaver is the Indiana Comm…
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NEJM Interview: Patricia Zettler on a proposed FDA rule on nicotine yields and potential challenges moving forward.
8:11
Patricia Zettler is a professor of law at The Ohio State University Moritz College of Law. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. P.J. Zettler, T.L. Wagener, and M.L. Berman. What’s Next for Nicotine? The Coming Legal and Political Battles over an FDA Proposal. N Engl J Med 2025;392:1461-1463.…
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Featuring articles on obinutuzumab in active lupus nephritis, tecovirimat for mpox, treatments for paroxysmal atrial fibrillation, and gene therapy for hemophilia B; a review article on enteral nutrition in hospitalized adults; a case report of a woman with cough and weight loss; and Perspectives on withdrawal of the United States from the WHO, on …
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NEJM Interview: John Patrick Co on a stipend program designed to address cost-of-living concerns for residency applicants.
5:14
John Patrick Co is vice president of education at Mass General Brigham and an associate professor of pediatrics at Harvard Medical School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. D.F. Weinstein, E. Olson, and J.P.T. Co. Addressing Socioeconomic Barriers to Residency Choice. N Engl J Med 2025;392:1353-135…
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Featuring articles on cancer-associated venous thromboembolism, endovascular treatment for stroke, dapagliflozin in patients undergoing TAVI, screening for prostate cancer, and extrachromosomal DNA; a review article on otitis media in young children; a case report of a woman with flank pain, fever, and hypoxemia; and Perspectives on some efforts to…
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Featuring articles on HIV prevention, left atrial appendage closure after ablation for atrial fibrillation, timing of thrombolysis for stroke, congenital diarrhea and enteropathy, and the association between wealth and mortality in the United States and Europe; a review article on malaria; a Clinical Problem-Solving describing a “hot” cardiomyopath…
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NEJM Interview: Rochelle Walensky on the increased workload and emotional and financial burden associated with applying to medical school.
13:26
Rochelle Walensky is the Bayer fellow in health and biotech at the American Academy in Berlin, a senior fellow at the Harvard Kennedy School, and an executive fellow at Harvard Business School. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. R.P. Walensky and L.D. Walensky. Application Overload — A Call to Reduc…
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NEJM Interview: Erin Fuse Brown on telehealth arrangements that have prompted concerns about inappropriate prescribing and unnecessary spending.
10:10
Erin Fuse Brown is a professor of health services, policy, and practice at the Brown University School of Public Health and a member of the Journal’s Perspective Advisory Board. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. E.C. Fuse Brown, O.J. Wouters, and A. Mehrotra. Partnerships between Pharmaceutical and…
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